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Lutein and Zeaxanthin: Pigments of the Macula Lutein and zeaxanthin are not precursors of vitamin A, but they can naturally accumulate in the eye especially in the macula, the area responsible for sharp central vision

Among over 20 distinct RCD modalities reported, ferroptosis, described as a ROS-dependent non-apoptotic iron-driven cell death [496], has attracted considerable attention as a potential therapeutic target in cancer [497]

In contrast, re-expression of MAPKAPK2 reversed these alterations, restoring Nrf2 nuclear localization and enhancing HO-1 expression (Figure 7D), consistent with activation of an antioxidant defense response

Risher, M