Understanding these dynamics helps you plan ahead and avoid being caught off guard by sudden availability changes
Randomized, double-blind, placebo-controlled, and replicated is strong
The study design followed the validated Wistar-Kyoto + chronic mild stress (WKY/CMS) framework, a translational model of treatment-resistant depression (TRD) that combines genetic vulnerability and environmental stress exposure
DOI: Published online: July 1, 2025 Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea Corresponding author: Hye Jin Yoo Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, 148 Gurodong-ro, Guro-gu, Seoul 08308, Korea E-mail: [email protected] Copyright 2025 Korean Diabetes Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited