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This highlights an important point: reducing cravings alone does not necessarily result in weight loss, especially without broader changes in diet, calorie intake, and physical activity

doi: 10.1016/j.biopha.2022.113611 160 WangKJiangLZhongYZhangYYinQLiSet al

In some embodiments, formulations or compositions described herein provide a constant, sustained, extended, delayed or pulsatile rate of release of an active agent into the inner ear environment and thus avoid any variability in drug exposure in treatment of otic disorders

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