The synthetic derivative of curcumin biphenyl-difluoroketone (EF24) has been reported to trigger cell apoptosis, restrain cell growth, and diminish metastatic capabilities (194, 195)
Blin K, Shaw S, Steinke K, Villebro R, Ziemert N, Lee SY, et al
Methods: An expert working group (EWG) comprising ten pulmonologists and a multidisciplinary drafting committee reviewed data from in vitro , mechanistic, animal and observational studies, randomized trials, reviews and meta-analyses for role of NAC in respiratory diseases
Sources conflict on whether fosgonimeton is a prodrug of Dihexa or a structurally distinct molecule, so it should not be read as evidence for or against Dihexa specifically only as the nearest human data point in the program, and a negative one