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The BMP/Smad pathway effect is counteracted by the transplantation of MSCs derived from bone marrow (BMSCs), which promote NSC differentiation into OLs, the myelinating glia of the CNS (Sandner et al., 2013

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FAQs The frequency of B12 injections varies: initially, they may be given weekly or biweekly to address severe deficiency, then reduced to monthly or less often for maintenance