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Los procedimientos de esta investigacin fueron de acuerdo a los lineamientos estipulados por la ley general de la salud en materia de investigacin en seres humanos, donde se aplic el consentimiento informado

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Hybridoma cells were subcloned five limiting dilution rounds to obtain the stable monoclonal cell clone MS4A 5E6 (rat IgG2c/)

Key molecular mechanisms encompass oxidative modification of critical proteins leading to dysfunction [361], membrane lipid peroxidation disrupting organelle integrity [362], mtDNA damage causing mitochondrial dysfunction [363], and depletion of key antioxidant molecules [364]