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The review further distinguishes between established outcome benefits (CVD, CKD, and OSA) and conditions still under investigation (neurodegeneration, arthritis, and some liver endpoints)
These findings also confirm the chronicity of obesity and suggest ongoing treatment is required to maintain improvements in weight and health." A new European consortium known as Sophia (Stratification of Obese Phenotypes to Optimize Future Obesity Therapy), led by scientists at University College Dublin, is now attempting to investigate this in more detail
PMID: 40609566 | doi:10.1016/S2213-8587(25)00092-0 Sinha B et al
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