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Consider the following approaches: Take naproxen with or after food to reduce direct gastric irritation Use the lowest effective dose of naproxen for the shortest duration necessary to manage your symptoms Discuss proton pump inhibitor (PPI) co-prescription with your GP if you require regular or prolonged naproxen usemedications like omeprazole or lansoprazole can significantly reduce the risk of NSAID-induced gastric ulceration Your GP may recommend a PPI if you: are aged 65 or over, have a history of peptic ulcer or gastrointestinal bleeding, are taking high-dose or prolonged NSAID therapy, are also taking medicines that increase bleeding risk (anticoagulants, antiplatelets, SSRIs, corticosteroids), or have significant comorbidities