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Sebecic et al., 1999) (and in other models, such as is observed with rat femoral head osteonecrosis ( ex vivo outgrowth of tendon fibroblasts from tendon explants, cell survival under stress, and the in vitro migration of tendon fibroblasts are the effects mediated by the activation of the focal adhesion kinase (FAK)paxillin pathway ( Similarly, as the next wound-healing focus with BPC 157 therapy (Sever et al., 2019) administered per-orally, continuously in drinking water, or intraperitoneally, alleviated rats showed bile duct ligation (BDL) and counteracted BDL-induced liver cirrhosis (Sever et al., 2019)

Other studies have found a positive relation between the fecal microbiome composition and grade of fibrosis in NAFLD: as such an abundance of Prevotella has been associated with advanced fibrosis [49]

10.1016/j.ecoenv.2022.113879 39 EckardtK

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