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Because NNMT occupies a central position within nicotinamide methylation pathways, it has become an important target for investigations involving enzyme regulation, methyl-donor utilization, cofactor-associated signaling networks, and methyltransferase pharmacology

From supporting the normal function of nerve cells to supporting the formation of red blood cells and DNA synthesis

NNMT participates in metabolic reactions involving nicotinamide and methylation processes, which are associated with cellular metabolic activity and biochemical pathway regulation