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On the practical question, the evidence points one way: combine at the point of use if at all one syringe or two, given close together and keep them as separate vials in storage, where there is no stability data to justify a pre-mixed blend

In general, RAIs are preferred over regular human insulin because of their more rapid onset and offset of action and association with a lower incidence of hypoglycemia [2, 3], although regular insulin may represent a pragmatic choice where costs or lack of resources limit availability [17]

Mostly Fitzsimmons because Fitzsimmons, he was a good buddy, and we did a lot of gigs together when we were starting out

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