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Metformin with GLP-RA Safe: Consistency with Prior Evidence These findings are consistent with earlier published evidence, a network meta-analysis of 34 RCTs across 10 GLP-1 RAs (n=12,993 patients) had previously confirmed that GLP-1 RAs added to metformin do not increase hypoglycaemia incidence and do not drive higher adverse event-related treatment discontinuation, lending further support to the favourable safety profile now confirmed through real-world pharmacovigilance data

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These FDA-approved medications work by regulating appetite, enhancing satiety, and improving metabolic health