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One of its primary actions is the activation of the Nrf2 pathway, which plays a vital role in cellular defense mechanisms

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The Biden administration placed restrictions on these and a handful of other peptides in 2023 moving them into a category that essentially prohibits compounding pharmacies from making the drugs

doi: 10.3389/fimmu.2026.1758379 Received 01 December 2025 Revised 05 March 2026 Accepted 05 March 2026 Published 28 April 2026 Volume 17 - 2026 Edited by Varun Sasidharan Nair, Italian Institute of Technology (IIT), Italy Reviewed by Mahmoud Abdelrahman Alkabbani, Egyptian Russian University, Egypt Lingjie Meng, Zunyi Medical University, China Updates Copyright 2026 Sivalingam