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The signal is promising but not definitive

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Jirapinyo P, Jin DX, Qazi T, Mishra N, Thompson CC

Variants in FTO (fat-mass and obesity-associated), GLP1R (the receptor every GLP-1 compound targets), MC4R (a satiety and energy-balance receptor), and TCF7L2 (tied to glucose handling and GLP-1 secretion) describe the terrain any compound acts on