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Some common signs of B12 deficiency include fatigue, weakness, pale skin, shortness of breath, dizziness, tingling or numbness in the hands and feet, difficulty walking, memory problems, and mood changes

Plasma and RBCs were aliquoted into separate vials and stored at -20C

This regulation is absent in c-Met-deficient primary mouse hepatocytes, leading to the overproduction of ROS, increased oxidative stress, and heightened sensitivity to apoptosis-promoting agents

Who should check with a provider first If you are pregnant, nursing, have kidney disease, or take medications that interact with B12 metabolism (such as metformin), discuss this with a provider before starting