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67,68 Specifically, female sex hormones including estradiol (e.g., 17-oestradiol) 69 protect female proopiomelanocortin (POMC) neurons from IR by enhancing POMC neuronal excitability and coupling insulin receptors to transient receptor potential (TRPC) channel activation
Effective blood sugar control and weight management can significantly reduce the risk of complications such as heart disease, kidney damage, and nerve problems
With a 20mg/ml vial, 1.25mg is just 6.25 units, a tiny draw that requires careful syringe reading but can dramatically reduce initial side effects for sensitive individuals
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