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In the Phase 2b NATIVE trial, lanifibranor showed meaningful improvement in liver fibrosis but caused mean weight gain of 2.4-2.7 kg, peripheral edema, and anemia

GLP-1 scale-up is more of a people problem than a capacity problem ( [22] )

doi: 10.4049/jimmunol.1004081 178 PatelASLinLGeyerAHaspelJAAnCHCaoJet al

Cardiovascular disease: Monitor blood pressure due to potential NO interaction Autoimmune disorders: Consider immune modulation risks with chronic peptide use Cancer history: Use with caution due to angiogenesis stimulation Always consult a healthcare provider if you have any preexisting medical condition or take prescription medications