weight loss drugs semaglutide What's New in Obesity Treatment? GLP-1 Drugs from the Gray

Effect of dulaglutide 3.0 and 4.5 mg on weight in patients with type 2 diabetes: exploratory analyses of AWARD-11

So in 2014, the FDA began approving these medications for weight loss first Saxenda (liraglutide) , then Wegovy (semaglutide) , Zepbound (tirzepatide) , and most recently, Foundayo (orforglipron)

Call 999 or go to your nearest A&E immediately if you experience: Signs of a serious allergic reaction (anaphylaxis) , including facial or throat swelling, difficulty breathing, a rapid heartbeat, or a widespread rash this is a medical emergency Severe difficulty breathing or collapse Contact your GP, NHS 111, or your trial medical team promptly if you experience: Persistent or severe vomiting or diarrhoea that prevents adequate fluid or food intake

It causes a transient rise in systolic blood pressure ($+6$ mmHg) and a slight drop in heart rate that lasts about 12 hours