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Quality assurance Surrogate spike recoveries (N = 5) for 17-estradiol-d5 and estrone-13C3 were 79 18% and 91 19% in tissues, respectively

[DOI] [PubMed] [Google Scholar] 60.Belhaj K, El Hyaoui H, Tahir A, et al

National Law Review (Polsinelli PC) was explicit on April 22, 2026: removing a Category 2 bulk drug substance does not, on its own, authorize use of that substance in compounding or bring it within FDAs interim enforcement discretion policy for substances in Category 1. Even Category 1 substances are only under enforcement discretion, which is short of full authorization

Additional tests may include full blood count (looking for macrocytic anaemia), methylmalonic acid, and homocysteine levels