The results of a transcriptomic analysis obtained from a mouse model also revealed that the stimulation of GLP-1 receptor by high doses of exendin-4 upregulates IGF-1R typically in pancreatic islets, thus reinforcing the concept that activating the IGF-1R/IRS-2/Akt pathway mediates the prevention of -cell loss under the control of incretins (40)
Neuroprotection in Rats Following Ischaemia-Reperfusion Injury by GLP-1 Analogues-Liraglutide and Semaglutide
Fang Y, Ji L, Zhu C, Xiao Y, Zhang J, Lu J, et al
Sin embargo, seal Krumholz, los medicamentos GLP-1 ms nuevos, que se administran como inyecciones semanales en lugar de diarias, han mostrado mayores beneficios, especialmente para pacientes con obesidad y an no estn disponibles como genricos