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14.2 BYDUREON BCISE Glycemic Control Trials in Adults with Type 2 Diabetes Mellitus BYDUREON BCISE versus BYETTA, Both as Monotherapy or as Add-on to Metformin, a Sulfonylurea, a Thiazolidinedione, or Combination of Oral Agents A 28-week, randomized, open-label comparator-controlled trial was conducted to compare the safety and efficacy of BYDUREON BCISE to BYETTA in adult patients with type 2 diabetes and inadequate glycemic control with diet and exercise alone or with oral antidiabetic therapy, including metformin, a sulfonylurea, a thiazolidinedione, or a combination of any two of these therapies (Trial 1 - NCT01652716)

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Most of the nausea resolves within four to six weeks as the body adjusts

Emphasizing safety and awareness of risks promotes a more informed approach to weight loss