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Modeling research published in PMC shows that modest weight loss reduces annual healthcare spending by approximately 15% per person, with effects rising in patients with higher baseline BMI and more comorbidities

The worldwide epidemiology of type 2 diabetes mellituspresent and future perspectives

Clinical trials particularly the PIONEER 3 and PIONEER 7 studies confirm that oral semaglutide is significantly more effective than sitagliptin for glycemic control and weight loss in patients with type 2 diabetes