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4 Potential effective therapies targeting ferroptosis for NAFLD 4.1 Ferroptosis inhibitors Fer-1 is a selective and potent inhibitor of ferroptosis, known for its ability to scavenge lipid radicals and prevent lipid peroxidation
Fat tissue stores environmental toxins, heavy metals, and lipophilic chemicals accumulated over years
pharmacological or genetic blockade of PPARa enhanced the anticancer activity of a ferroptosis inducer in mice, suggesting its potential as a metabolic target to overcome drug resistance [56]
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