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A useful overview of that link is in microbiota-immune, which explains how microbes steer immune behavior

The number of studies examining newer medicines like semaglutide and tirzepatide remains relatively small, and follow-up durations after stopping medicines were generally short, meaning some estimates are modelled projections beyond observed follow-up

GLP-1 drugs have obviously been all the rage for weight loss, and there has been some off-label use of them to treat liver disease like MASH, but in the Phase III ESSENCE trial, after 72 weeks, 63% of patients on Wegovy saw their steatohepatitis resolved without any worsening of fibrosis, compared to just 34% with placebo

Cell 7 , 683694 (2001)