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Any consideration of investigational approaches should occur only within the context of clinical trials or with explicit acknowledgment of the limited evidence base and careful risk-benefit assessment tailored to your specific clinical circumstances

Reconstitution steps Begin by cleaning your work surface thoroughly

non-GLP-1 users

Contact your GP or diabetes care team within a few days if: You develop new or worsening acne that does not respond to over-the-counter treatments within 4-6 weeks Skin changes are causing significant distress or affecting your quality of life You notice unusual skin changes such as persistent discolouration, new lumps, or changes in existing moles Injection site reactions persist beyond a few days or occur repeatedly at different sites Your healthcare professional can assess whether skin changes are related to Ozempic, require specific treatment, or might indicate another underlying condition