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Incorporating NET biomarkers into clinical protocols could enable patient stratification and guide targeted NET-modulating therapiessuch as PAD4 inhibitors, DNase, or antioxidantsin combination with standard-of-care interventions, ultimately improving metabolic and reproductive outcomes

Finally, the distribution of senescent cells varies in different tissues and organs

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Another significant group includes carotenoids such as beta-carotene, lutein, and zeaxanthin, which are found in colorful fruits and vegetables like carrots and spinach [203]