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Participants taking the highest dose of retatrutide saw, on average, the following health improvements: these average reductions in cardiovascular disease risk factors: 37 percent reduction in triglycerides, or fats in the blood 16.5 percent reduction in non-HDL bad cholesterol 9.3 mmHg reduction in systolic blood pressure, the pressure in the arteries when the heart beats 7.5-inch reduction in waist circumference 51.2 percent reduction in high-sensitivity C-reactive protein, a measurement of inflammation in the body Side Effects Led More Than 1 in 10 Participants to Drop Out Side-effect rates differed between the two trials

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Box 38558 Booysens 2016 DISTRIBUTOR: VIRBAC RSA (Pty) Ltd (Reg

Patients with certain GLP-1 receptor variants may experience rapid satiety onset, while those with FTO variants linked to higher baseline hunger may benefit from an earlier dose increase or combination therapy