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If you carry an unfavorable GIPR tolerability variant, you may experience more nausea on this drug than on a GLP-1-only conjugate
Side Effects Comparison# Pemvidutide Side Effects# GI adverse events were consistent with the GLP-1 class in Phase 2 trials, generally well tolerated
Patients typically report feeling satisfied with smaller portions and experiencing less frequent hunger between meals
In addition, further research is needed to clarify potential sex-specific differences and to better understand the central and peripheral mechanisms of action of GLP-1 and amylin analogues, including whether their effects are additive, synergistic, or potentially divergent in different clinical contexts
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