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THE CLINICAL PROBLEM Acetaminophen (known as paracetamol outside the United States) is a commonly used analgesic and antipyretic agent, and its use is one of the most common causes of poisoning worldwide

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Epidemiology 19(6):766779 Funding This study was funded by the National Institute on Aging (AG07664, AG057557, AG061388, and AG062272), the National Institute on Alcohol Abuse and Alcoholism (AA029831)

Nausea is the most common side effect, affecting approximately 15-30% of patients depending on the dose, followed by diarrhea (13-16%), vomiting (6-12%), and constipation (6-7%)