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Rosa Caballero, stated that the allergens involved in vitamin B12 reactions is likely to be a hapten, a small molecule that can trigger an immune response when it binds to a larger carrier protein

They go on to state that pregnant women are usually deemed a priority group for getting vaccinations in general, as pregnancy in and of itself does cause some degree of immunocompromise, and pregnant women who get COVID are at increased risk of developing severe illness and have increased risk of negative pregnancy outcomes, including but not limited to preterm birth

PMID 35778579

Individuals who lack intrinsic factor have no ability to absorb vitamin B 12