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However, the study found that semaglutide also affects body fat distribution and adipocyte characteristics: semaglutide led to a reduction in adipocyte size and macrophage infiltration, an increase in molecular markers of adipocyte browning along with improved mitochondrial biogenesis, and a decrease in endoplasmic reticulum stress

Increases muscle mass: Creatine promotes water retention in muscle cells, making muscles appear fuller and can also lead to longer-term gains by enabling harder training