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Pancreatic -Cell Biology Research In cultured isolated pancreatic islets and cell lines, the compound is applied to analyze how oral GLP-1R agonists impact insulin secretion, -cell survival, and the expression of function-associated genes (like PDX-1, MafA, and insulin genes)

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While some studies attribute beneficial effects of weight loss and amelioration of metabolic syndrome to Oscillospira , an increased abundance has also been linked to a high-fat diet in different rodent models as well as diabetes and inflammation in type 2 diabetes rat models [56, 58]