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Most frequent causes of acute cholangitis are biliary calculi (2870%), benign biliary stricture (528%), and malignancy (1057%)

(3) Old Age (60 years): reduced adaptability and higher deficiency risk Older adults have lower gut microbiota diversity and reduced fiber fermentation efficiency, making even mild nutrient deficiencies impactful: A cross-sectional study involving 297 elderly individuals aged 60 years and older (144 males and 153 females) was conducted to assess the relationship between zinc status and the presence of depression or anxiety, using validated scales and diagnostic tools