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Understanding these motivations helps clinicians provide individualized guidance for safe discontinuation when appropriate, while also addressing modifiable barriers that might allow continued therapy when clinically beneficial

Lee: GLP-1 agonists primarily affect the gastrointestinal system, but they also act on the brain, particularly the hypothalamus, which regulates many core functions, including hormones, temperature, and appetite

Dosing flexibility allows providers to titrate doses in smaller increments than branded pens, which may reduce side effects during initiation

Taken together, these findings indicated that hepsin / mice experience heightened oxidative stress in the early stages of APAP exposure, suggesting that endogenous hepsin might protect against toxicity during the early stages of APAP exposure, thereby significantly influencing survival outcomes in drug-induced toxicity cases