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They can tell you: Whether to take your dose before departure or after arrival How to adjust across 5 or more time zones What to do if your routine is disrupted mid-trip A simple approach some semaglutide users follow: Traveling east (losing time): take your dose 1 day earlier before departure Traveling west (gaining time): take your dose 1 day later after arrival Small time shift of 1-3 time zones: stay on your home schedule for the first week, then adjust gradually Write your dose schedule on paper or in a phone note before you leave

Unfortunately, evidence 31 shows that drastic and rapid weight losswhether from GLP-1 RA use, bariatric surgery, or diet-induced methodscan reduce LBM by up to 50% of the total weight lost