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In another study, compared to the control group, GHK treatment groups (1 or 10 mg/kg) demonstrated decreased neuronal apoptosis and neurological deficits in rat brains induced by intracerebral hemorrhage (ICH) injury

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Global analysis of the mitochondrial proteome in response to cellular GSH depletion To identify mitochondrial proteins regulated by GSH availability, we used quantitative proteomics and analyzed mitochondria immunopurified from HeLa cells expressing a mitotag (3XHA-OMP25-mCherry) grown in standard media or treated with the glutathione synthesis inhibitor, buthionine sulfoximine (BSO) 13

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