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Could it have unforeseen effects on organ function

The review also notes that some patients may require temporary adjustments to their GLP-1 medications before undergoing oral surgery because of delayed gastric emptying and anesthesia considerations

Nevertheless, body weight and visceral fat area showed significant reductions only in the ipragliflozin group compared with the pioglitazone group [49]

We already know from two-year follow-up studies of patients who have taken injectable GLP-1 drugs for at least six months that net weight loss in the real world is as little as 4.7% for many reasons, including poor adherence as a result of side effects, supply and affordability