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Main exclusion criteria included BMI 20 kg/m, type 1 diabetes mellitus, type 2 diabetes mellitus, previous treatment with insulin or with oral hypoglycemic or insulin-sensitizing agents, history of malignancy, and hypopituitarism
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Typically, CAFs overexpress alpha-smooth muscle actin (-SMA), Vimentin, platelet-derived growth factor receptor (PDGFR), PDGFR, Tenascin-C, Caveolin 1, fibroblast activation protein (FAP), and ferroptosis suppressor protein 1 (FSP1) [66]
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