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Steroid profiling reveals widespread local regulation of glucocorticoid levels during mouse development

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The relevance of an appropriate consumption of trace elements such as Se is due to its antioxidant and anti-inflammatory effect, since it has been reported that these patients have an increase in the physiological concentrations of reactive oxygen species (ROS) that can cause damage to cellular components, including proteins, lipids and DNA, that promote the destruction of cartilage and bone [11,12,13]