Although autonomic and peripheral GLP-1R+ neurons, including those within the nodose ganglion, may partially contribute to the weight loss actions of peripherally administered GLP-1RA [74, 82], ablation of CNS neurons targeted by nestin - Cre or Wnt1 - Cre abolishes the anorectic actions of peripherally administered GLP-1RA in mice [74, 83]
As with many organs, lung diseases vary significantly in their etiology and pathology, ranging from inherited genetic diseases like cystic fibrosis (CF), to allergic and inflammatory disorder diseases, such as asthma and chronic obstructive pulmonary disease (COPD)
Original Article: TripleHormone-Receptor Agonist Retatrutide for Obesity A Phase 2 Trial nej.md/3JoNIh6 #Endocrinology 2
They also reduce visceral and ectopic fat that accumulates around the abdomen and organs, which may help curb the inflammatory and metabolic signals that promote aging