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That distinction matters because ipamorelin is studied for its ability to trigger a receptor-mediated pulse, not for acting like a bulk replacement hormone

The missing values in this filtered data table were imputed with the R package missForest with default settings (70), using a random forest trained on the available data values to predict the missing data points

Downregulated metabolites included glutamine, isoleucine, deamido-NAD + , and the upregulated metabolites included acylcarnitines, succinyladenosine, and leukotriene B4

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