Beyond pharmacology, real-world choice is shaped by cost, convenience, and tolerance for needles
Pernicious anemia is a condition where the body cannot absorb vitamin B12
NICE guidance suggests alternate-day dosing may improve absorption and reduce side effects if daily dosing is not tolerated Absorption tips : Take iron on an empty stomach if possible, avoid tea, coffee, milk or antacids within 1-2 hours of taking iron, and consider taking with vitamin C (e.g., orange juice) to enhance absorption Side effects : Gastrointestinal symptoms including nausea, constipation, diarrhoea, and black stools are common
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