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A 2025 comprehensive review in Medical Science Monitor covering studies from 20162025 confirmed that GHK-Cu-based formulations enhance fibroblast migration, ECM remodelling, collagen and elastin synthesis, and wound closure across multiple model types

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Its ability to modulate gene expression, promote balanced tissue remodeling, and support regenerative processes makes it particularly interesting for wound healing, skin rejuvenation, and potentially neurodegenerative conditions

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