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NaB-enhanced hepatic GLP-1R expression via inhibiting HDAC It has been reported that short-chain fatty acids (SCFAs) including NaB are able to regulate the immune response and metabolism through the activation of GPRs, such as GRP43 and GRP109a or through the inhibition of HDAC 27,28

CBD is an allosteric modulator of both -opioid receptors and -opioid receptors at high concentrations, altering the efficacy of which opioid agonists bind or dissociate from the receptors (Vaysse et al

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