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In a controlled study, patients (121 years of age) with newly diagnosed ALL or lymphoblastic lymphoma were given pegaspargase (2500 IU/M2, once induction, 15 doses every 2 weeks starting at week 7) or calaspargase pegol (2500 IU/M2, once induction, 10 doses every 3 weeks starting at week 7)

Eluate was monitored by an electrochemical four-channel colorimetric sensor (ESA model 6210) at 700, 800, 900 and 1000 mV

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I havent noticed any of this in my own bottle after about a year of irregular use