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Merck had other China deals in the last few months (LaNova Medicines and Curon Biopharmaceutical), but all deals are either early-stage (ongoing Phase 1) or pre-clinical (Hansoh)

The exception is dose escalation steps each increase in dose often brings a temporary return of mild gastrointestinal symptoms that typically resolve within one to two weeks

By this point, most users have developed a rough sense of whether their symptoms are manageable or problematic

Scrotal ultrasound provides information about testicular size, volume, density, and blood flow, and can detect or confirm a testicular mass, absence of vas deferens, epididymal abnormalities, and varicocele