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7 studies

Additionally, the promoter of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PGC-1/PPARG) has two AREs, although they have not been validated as functional, and has been reported to be both up- and downregulated by NRF2 activation depending on the context (OBrien et al., 2015)

Keeping your muscle strong helps protect your metabolism, burn calories more efficiently, and makes it easier to lose weight and keep it off long-term

32,33 As IBD often begins in youth, it may hinder peak bone mass acquisition and elevate adult fracture risk

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