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Description

Retatrutide works similarly to tirzepatide, acting as a glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) agonist

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That broad agonist activity makes it a useful tool when researchers want to compare the response of these receptors with each other or calibrate the sensitivity of a test model

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2025;48(Suppl 1):S167-S180

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2.2 Historical reasons for underexploration Across peptide systems, several recurring factors have contributed to underexploration

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