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Finally, 20 pregnancies (18%) were electively terminated, with 6 of these terminations (5.4% of total) citing fetal abnormalities as the reason and 14 terminated for other reasons

A study published in Circulation noted that while these reductions in muscle volume appear proportionate to the weight loss achieved, the concern remains that excessive lean mass loss could lead to sarcopenia, reduced metabolic rate, and poorer long-term outcomes

Patients who maintain results beyond 12 weeks adjust intake downward as weight decreases and incorporate refeed strategies to manage leptin suppression