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The bear case: the core growth engine faces systemic pressure Regulatory risk becomes the new normal: the FDAs stance may be only the beginning, and the compounded-drug model could remain under sustained pressure

2, Tables 1, 3)

The presence of GLP-1 receptors in testicular tissue and evidence of direct, weight-loss-independent effects on sperm function raises the possibility that GLP-1 drugs may act on male reproductive biology through two distinct mechanisms simultaneously: one systemic (through metabolic improvement) and one local (through direct testicular signaling)

[DOI] [PubMed] [Google Scholar] 125.Saxena A.R., Banerjee A., Corbin K.D., Parsons S.A., Smith S.R